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Table 4 Loci encoding well-characterized peptide products, with the highest 5 % πN value between the Kiambu5 stock and the Muguga reference sequence. Variants in hypothetical proteins, and those not in the highest 5 % πN can be found in Additional file 3: Table S3

From: The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence

Locus Tag / 2005 Locus Tag IDa Product Name Domains Protein Localization/ Confidencec πNd πN/πSd Synd Non-synd
TP01_0066 TpMuguga_01g00066 50S ribosomal protein L33 - S/ 1 0.013 0.4313 3 3
TP01_0248 TpMuguga_01g00248 tRNAHis guanylyltransferase 1 TMb _/ 1 0.0148 0.4679 8 10
TP01_0272, TP01_0273 TpMuguga_01g00272 Kinase binding protein CGI-121 - _/ 1 0.0161 0.3261 7 8
TP01_0374 TpMuguga_01g00374 DEAD/DEAH box helicase - _/ 2 0.0131 0.3503 13 15
TP01_0405 TpMuguga_01g00405 Asparagine synthetase domain-containing protein C4F6.11c - _/ 1 0.0121 0.4375 14 15
TP01_1056 TpMuguga_01g01056 Merozoite Antigen 1 GPI S/ 2 0.0125 1.1773 3 8
TP01_1165 TpMuguga_01g01165 ATP-dependent RNA helicase SUV3 homolog mitochondrial - M/ 5 0.015 0.3049 25 23
TP01_1173, TP01_1174 TpMuguga_01g01174 Ribonuclease P protein subunit p29 - _/ 3 0.0123 0.255 7 7
TP01_0275, TP01_0273, TP01_0274, TP01_0272 TpMuguga_01g02345 Phosphatidylinositol 4-phosphate 5-kinase 7 - _/ 4 0.0142    3
TP01_1063 TpMuguga_01g02455 Uncharacterized protein C18H10.09 - _/ 1 0.0132 0.66 2 4
TP02_0369 TpMuguga_02g00369 Dual specificity protein phosphatase 12 - _/ 2 0.0142 0.3435 11 11
TP03_0010 TpMuguga_03g00010 Archease protein family (MTH1598/TM1083) - _/ 1 0.0143 0.4618 6 8
TP03_0595 TpMuguga_03g00595 Ydr279p protein family (RNase H2 complex component) - _/ 2 0.0187 0.5673 5 13
TP03_0601 TpMuguga_03g00601 CobW/HypB/UreG nucleotide-binding domain - _/ 3 0.0127 0.4562 9 10
TP03_0270 TpMuguga_03g02310 Protein CyaY - _/ 5 0.0117 0.2878 36 35
TP04_0705 TpMuguga_04g00705 Maf-like protein - _/ 3 0.0115 0.5954 5 6
  1. The previously identified antigen p32 is marked in bold
  2. aLocus Tag Identifiers according to the updated whole genome gene structural re-annotation
  3. bNumber of transmembrane domains
  4. cProtein localization predictions based on TargetP: C = chloroplast; M = mitochondrion; S = Secretory pathway; _ = Any other location. Prediction confidence: 1 = max; 5 = min
  5. dSNPs between Kiambu5 and the reference Muguga isolate