Fig. 5

The EXT-to-core transition is associated to a shift of GC % average values. a The GC % is calculated over one horizon (windows size 500 bp) along the sequence of chromosome II. All chromosome extremities are characterised by a high GC content in E. cuniculi. The transition with the central part of the chromosome is improved by the bell-like shape of the GC % curve over the coding core region. The GC % values are high at the centre of the molecules. The GC content of the chromosome core sequence diminishes progressively from the centre to the end by accumulation of local minima. The chromosome II is represented in a opposite orientation. b EXT1 repeat in a GC rich region at IIβ extremity (shaded region in A). All EXT repeats (except EXT7) are associated with high GC % values. After touching its minimal value, the GC-curve is growing more or less rapidly depending on extremities when EXT sequences are read in a core to telomere orientation. The IIβ extremity is part of extremities presenting a slow growing curve at the EXT-to-core transition. c EXT-to-core transitions are associated to low GC %. The GC % minimum value was plotted in function of the EXT-to-core transition for each extremity. Coordinates were calculated from the corresponding end of the consensus sequence