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Fig. 7 | BMC Genomics

Fig. 7

From: Subtelomere organization in the genome of the microsporidian Encephalitozoon cuniculi: patterns of repeated sequences and physicochemical signatures

Fig. 7

Genomic landscape of Encephalitozoon cuniculi. GC and AT base composition skews were evaluated simultaneously using a 2D representation where the curve is drawn while reading the sequence from the 5-prime to 3-prime end. The course of the curve is obtained by going up for a G and down for a C and left or right whether an A or a T was read respectively. The evolution of GC and AT skews is similar for the 11 chromosomes of E. cuniculi. In a 2D representation, the core of the molecule presents a globular structure whereas the EXT and SUB sequences are characterized by G enrichment (in a core to telomere orientation). The AT skew is in an opposite way between EXT repeats and SUB region. The distal end of the SUB region is composed of repeats which present a T accumulation only. The compactness of the coding core regions of E. cuniculi chromosomes is apparently higher than thus observed in a random sequence (bottom right curve). Horizontal and vertical discontinuous lines indicate the zero position on the ordinate and abscise respectively. The two lines get cross at the first base in 5-prime of the consensus sequence deposited in the database

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