Transfer RNA detection by small RNA deep sequencing and disease association with myelodysplastic syndromes

BMC Genomics

Table 2 Linear regression results on tRNAs and treatment association

	tRNA	Effect^a	p value
Treatment Response R-squared = 0.67	chr6.tRNA157.ValCAC	0.0149	0.0356
	chr11.tRNA17.ValTAC	0.1415	0.8343
	chrM.tRNA12.TS1	−0.4023	0.0136
	chrX.tRNA4.ValTAC	−0.0058	0.9931
Post vs Pre R-squared = 0.40	chr1.tRNA35.GlyGCC	−12.9856	0.3134
	chr19.tRNA9.PseudoTTT	0.0038	0.0507
	chr21.tRNA2.GlyGCC	12.9798	0.3136

Notice that not all tRNA are significant in this table; however, acting together, they explain the greatest amount of variation in treatment
^aEffect is explained as per 1 unit increase in tRNA expression; the treatment changes the effect amount of unit

ISSN: 1471-2164