Fig. 4

Phages of PST2 are related to those from strains associated with high HUS rates. Host strain names or phage names are indicated. Phage genomes were cut into 500 bp fragments. The “Core genome” was defined as fragments present in >2 phage genomes at > 85 % identity using Panseq [39]. The presence or absence of core genome fragments in each phage genome was used for clustering. Uncorrected P-distance was used to build a neighbor-joining tree using SplitsTree 4 [80]. PST1, PST2, and PST3 clusters are highlighted by yellow, light purple and orange shading, respectively