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Table 1 Genes that constitute the 7-gene and 5-gene signature for ADC and SCC

From: Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations

Signature

Gene name

Cytoband

DNA copy numbera

Poor prognosisb

Good prognosisb

ADC

YES1

18p11.32

0.11

−0.18

TYMS

18p11.32

0.11

−0.19

HMGN1

21q22.2

−0.12

0.11

PSMA4

15q25.1

0.01

−0.23

MYO1E

15q22.2

−0.04

−0.19

POFUT2

21q22.3

−0.13

0.10

SLC25A20

3p21.31

−0.08

−0.27

SCC

GPD1L

3p22.3

−0.41

−0.24

TRA2B

3q27.2

0.66

0.72

CTNND1

11q12.1

−0.21

0.07

DICER1

14q32.13

0.13

−0.23

ZNF292

6p14.3

0.04

−0.14

  1. aMean gene copy number data (in log2ratio) are shown for the training set
  2. bPatients with a risk score greater (smaller) than the median are considered patients with poor (good) prognosis
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BMC Genomics

ISSN: 1471-2164

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