Fig. 5
From: Identifying binary protein-protein interactions from affinity purification mass spectrometry data
Assessment of inferred direct interactions using the SGD complexes. Interactions are ranked by scores calculated using corresponding methods. Performance of all methods is measured by plotting the number of top-ranking inferred direct interactions of a method against the number of complexes that are sufficiently connected by these interactions. A complex is considered to be sufficiently connected by a set of physical interactions if the physical interactions reduce the number of connected components within the complex to less than 50 % compared with the unconnected complex. a Collins dataset, b Friedel dataset