Encyclopedia of bacterial gene circuits whose presence or absence correlate with pathogenicity – a large-scale system analysis of decoded bacterial genomes

Table 2 KEGG reference pathways, which are statistically enriched by orthologs abundant in antibiotics-resistant bacteria. Hypergeometric test assumes as background the set of pathogen-linked orthologs.

Pathway	p value via hypergeometric test
D-Arginine and D-ornithine metabolism	0.00572
Amino sugar and nucleotide sugar metabolism	0.0273
Peptidoglycan biosynthesis	0.00135
Sphingolipid metabolism	0.00524
Aminoacyl-tRNA biosynthesis	0.00076
Phosphatidylinositol signaling system	0.04909
PI3K-Akt signaling pathway	0.00384
Amoebiasis	0.03099

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