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Table 8 Significant pathway in term of biological process of GO database

From: Dynamic association rules for gene expression data analysis

ALL > AML (−1 to AML) in association rule

 

ALL > AML in t-test

 

Biological Process

P-value

Biological Process

P-value

Metabolic process

5.05E–25

Metabolic process

8.38E–25

Primary metabolic process

1.65E–21

Primary metabolic process

2.80E–23

Nucleobase-containing compound metabolic process

2.20E–13

Nucleobase-containing compound metabolic process

3.20E-21

Cell cycle

5.27E–07

DNA metabolic process

3.23E–16

Protein metabolic process

1.30E–06

Cell cycle

1.41E–13

DNA metabolic process

3.88E–06

DNA repair

7.06E–10

Cellular component organization or biogenesis

1.59E–04

DNA recombination

6.09E–08

Cellular process

2.00E–04

Cellular process

1.10E–07

Chromatin organization

7.37E–04

DNA replication

4.00E–07

RNA metabolic process

1.01E–03

Response to stimulus

4.04E–07

Organelle organization

3.10E–03

mRNA processing

2.10E–06

Cellular component organization

5.49E–03

RNA metabolic process

2.70E–06

DNA repair

7.40E–03

Cellular component organization or biogenesis

5.52E–06

Protein complex biogenesis

1.61E–02

response to stress

6.65E–05

Protein complex assembly

1.61E–02

Cellular component organization

1.73E–04

DNA recombination

3.09E–02

Protein metabolic process

2.75E–04

DNA replication

3.10E–02

Organelle organization

3.43E–04

Transcription from RNA polymerase II promoter

4.21E–02

Purine nucleobase metabolic process

8.90E–04

Transcription, DNA-dependent

4.84E–02

Protein phosphorylation

1.03E–03

  

mRNA splicing, via spliceosome

1.40E–03

  

Meiosis

3.33E–03

  

Chromatin organization

4.12E–03

  

RNA splicing

8.94E–03

  

RNA splicing, via transesterification reactions

8.94E–03

  

Cellular defense response

2.28E–02

  

Cell proliferation

3.93E–02

  

Nitrogen compound metabolic process

4.54E–02

  

Transcription, DNA-dependent

4.63E–02

  

Regulation of carbohydrate metabolic process

4.66E–02

AML > ALL (+1 to AML) in association rule

 

AML > ALL in t-test

 

Biological Process

P-value

Biological Process

P-value

Metabolic process

1.20E-10

Cellular process

1.14E-02

Cell communication

8.26E-10

  

Developmental process

3.19E-09

  

Cellular process

5.32E-09

  

Immune response

6.40E-09

  

Immune system process

4.00E-08

  

Primary metabolic process

5.37E-08

  

Macrophage activation

1.43E-07

  

Response to stimulus

1.71E-07

  

System development

8.39E-06

  

Cell death

6.55E–05

  

Apoptotic process

6.55E–05

  

Death

7.05E–05

  

Proteolysis

2.85E–04

  

Hemopoiesis

6.24E–04

  

Protein metabolic process

1.30E–03

  

Negative regulation of apoptotic process

1.51E–03

  

Transport

4.90E–03

  

Localization

8.73E–03

  

Biological regulation

9.95E–03

  

Angiogenesis

1.46E–02

  

Regulation of biological process

2.34E–02

  

B cell mediated immunity

7.41E–02

  

Skeletal system development

8.16E–02

  

Cellular defense response

8.65E–02

  

Mesoderm development

9.51E–02

  
  1. Bolded terms indicate the significant pathways appeared in both DAR and t-test