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Table 4 Accuracy of Jitterbug and RetroSeq at detecting homozygous (HOM) and heterozygous (HET) TEI, and predicting their zygosity, in simulated human dataset (simulated reads)

From: Jitterbug: somatic and germline transposon insertion detection at single-nucleotide resolution

  Coverage TP FP FN PPV (%) Sensitivity (%) Accurate Zygosity (%) HET detected (%) HOM detected (%)
Jitterbug 10X 2693 1 579 99.96 82.3 94.83 78.52 86.08
  20X 2825 0 447 100 86.34 99.58 84.58 88.10
  40X 2919 0 353 100 89.21 100 88.25 90.17
RetroSeq 10X 1308 23 1964 98.27 39.98 - 8.51 71.37
  20X 2528 115 744 95.56 77.26 - 72.28 82.23
  40X 2754 258 518 91.43 84.17 - 81.70 86.63