Fig. 5
From: Bacterial transcriptome reorganization in thermal adaptive evolution
Epistasis in transcriptome between heat shock and genome mutation. a Scatter plots of the changes in gene expression mediated by heat shock and genotype. The heat shock-induced changes in gene expression (ΔHSA) are plotted against the genotype-mediated changes in gene expression (ΔG) at the regular temperature. Both changes are based on the ancestor (Anc). Correlation coefficients (r) and p-values (p) are indicated. b Negative epistasis. The additive changes in gene expression (ΔHSA + ΔG) are plotted against the simultaneous changes (Δ(G + HSA)), which represent the changes in gene expression between the evolved strains at the heat shock temperature (41B_hs, 43B_hs and 45L_hs) and the ancestor under the regular temperature (Anc_r). The red line indicates linear regression. The values with slopes subtracted from 1 are indicated, representing the magnitudes of the negative epistasis. Gene expression is in log-scale