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Table 2 Summary of all mutations called using three different thresholds

From: Characterizing Benzo[a]pyrene-induced lacZ mutation spectrum in transgenic mice using next-generation sequencing

   Independent Mutations Total Mutations aMutants Removed
  Threshold bBase Subs. cIns dDels Base Subs. Ins Dels Base Subs. Ins Dels
Control Stringent 127 3 22 542 7 34 14 101 117
  Medium 159 7 27 574 7 39 18 193 223
  Low 190 12 36 605 16 48 55 426 420
BaP Stringent 637 41 176 1583 66 428 108 750 577
  Medium 767 60 239 1714 85 493 183 1139 818
  Low 921 125 338 1869 151 593 374 1846 1284
  1. aMutants removed refer to the number of variants that passed the threshold in one technical replicate but not the other
  2. bBase substitutions
  3. cInsertions
  4. dDeletions
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BMC Genomics

ISSN: 1471-2164

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