Table 3 Results for the top 30 gene-annotated autosomal DMPs associated with sex in CHAMACOS newborns
From: Sex differences in DNA methylation assessed by 450 K BeadChip in newborns
ProbeID | Gene symbol(s) | Chromosome | Positiona | βGirl (M-value) | P-value | Girl mean (% methylation) | Boy mean (% methylation) |
|---|---|---|---|---|---|---|---|
cg03691818 | KRT77 | 12 | 53085038 | 2.38 | 1.84E-43 | 11.9 | 3.0 |
cg26921482 | AMDHD2 | 16 | 2570283 | 1.72 | 2.43E-43 | 43.8 | 20.1 |
cg17743279 | CDK6 | 7 | 92463268 | 1.84 | 4.04E-31 | 3.1 | 1.0 |
cg07852945 | TLE1 | 9 | 84303915 | 0.93 | 7.30E-31 | 14.0 | 7.8 |
cg26355737 | TFDP1 | 13 | 114292172 | −0.95 | 7.57E-29 | 80.6 | 88.5 |
cg25568337 | ARID1B | 6 | 157098338 | 0.68 | 1.36E-26 | 21.2 | 14.6 |
cg05100634 | SMAD2 | 18 | 45457604 | 1.77 | 2.91E-26 | 2.4 | 0.9 |
cg03608000 | ZNF69 | 19 | 11998623 | 0.86 | 1.76E-24 | 5.5 | 3.1 |
cg02325951 | FOXN3 | 14 | 89878619 | −0.72 | 4.04E-24 | 62.4 | 73.0 |
cg17612569 | GABPA;ATP5J | 21 | 27107221 | −3.07 | 7.86E-24 | 1.0 | 6.8 |
cg04874129 | SLC6A2 | 16 | 55690873 | 0.75 | 9.82E-23 | 14.1 | 9.0 |
cg08906898 | RBM39 | 20 | 34319899 | −0.92 | 2.66E-22 | 87.2 | 92.6 |
cg04946709 | LOC644649 | 16 | 59789030 | −0.73 | 3.58E-22 | 70.1 | 78.8 |
cg02989351 | YWHAQ | 2 | 9770584 | 0.37 | 1.90E-20 | 16.5 | 13.2 |
cg12204423 | PHF17 | 4 | 129732568 | −0.82 | 1.94E-20 | 5.0 | 8.3 |
cg25304146 | WBP11P1 | 18 | 30092971 | −0.49 | 4.64E-20 | 57.6 | 64.9 |
cg22345911 | CSNK1D | 17 | 80231263 | 1.18 | 5.43E-20 | 5.2 | 2.7 |
cg01906879 | GBE1 | 3 | 81811016 | 0.54 | 4.17E-19 | 8.5 | 6.0 |
cg06152526 | PLLP | 16 | 57290525 | −0.62 | 5.25E-19 | 69.8 | 77.5 |
cg04190002 | SHANK3 | 22 | 51113604 | 0.40 | 5.35E-19 | 33.8 | 27.9 |
cg06644124 | ZNF281 | 1 | 200379083 | 0.50 | 6.63E-19 | 31.4 | 25.1 |
cg07628841 | GPN1;CCDC121 | 2 | 27851430 | 0.30 | 7.09E-19 | 42.3 | 37.3 |
cg23001456 | KIAA0664 | 17 | 2615074 | 0.86 | 7.47E-19 | 4.5 | 2.8 |
cg26213873 | CTTNBP2NL | 1 | 112939056 | 0.41 | 3.34E-18 | 8.6 | 6.6 |
cg25438440 | CLDND1 | 3 | 98241168 | 0.55 | 3.72E-18 | 6.1 | 4.2 |
cg07816873 | ERC1 | 12 | 1100472 | 0.54 | 3.88E-18 | 23.4 | 17.5 |
cg24016844 | C1orf103 | 1 | 111506641 | −0.43 | 1.28E-17 | 7.4 | 9.6 |
cg11841231 | PARD3B | 2 | 205543309 | −0.68 | 5.39E-17 | 79.8 | 85.9 |
cg13323902 | VTRNA1-1 | 5 | 140090859 | 0.53 | 6.23E-17 | 26.0 | 19.8 |
cg12900929 | PRDM4 | 12 | 108154862 | 0.83 | 1.41E-16 | 11.2 | 6.9 |