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Table 3 Comparison of in silico and in vivo growth rates of S. limacinum

From: Reconstruction and analysis of the genome-scale metabolic model of schizochytrium limacinum SR21 for docosahexaenoic acid production

Media condition

Growth rate (/h)

(mmol/gDW/h)

In vivo

In silico

glucose (v = 1.4)

0.0887

0.0812

glucose (v = 1.4, DHA production = 0.03)

0.0883

0.0738

glycerol (v = 1.6)

0.0620

0.0613

  1. In vivo: experimental results, In silico: simulation results. In vivo growth rate was calculated from the growth curve of S. limacinum. In silico growth rate was the solution of S (m × n) matrix, when the biomass function was used as objective function