Table 1 Effects of the differences between BWA and Bowtie 2 alignments on the accuracy of variant calling in simulated data set

Maximum sensitivity of VariantMetaCaller

0.028

0.027−0.029

2.2×10⁻¹⁶

0.044

0.042−0.046

2.2×10⁻¹⁶

Precision at maximum sensitivity

0.009

0.007−0.01

2.2×10⁻¹⁶

0.039

0.025−0.053

8.6×10⁻⁷

AUPRC of VariantMetaCaller

0.028

0.027−0.029

2.2×10⁻¹⁶

0.042

0.040−0.044

2.2×10⁻¹⁶