Number or | Data set |
---|
proportion of | Simulated | | Experimental |
---|
transcripts | s1 | s2 | s3 | | Mouse | Rat | Bee | Human |
---|
Total | 9000 | 9000 | 9000 | | 18646 | 15923 | 14400 | 43256 |
Crit. >8 | 9000 | 9000 | 9000 | | 8554 | 6264 | 13761 | 12348 |
Sign VC | 1 | 1794 | 6704 | | 4329 | 6 | 7093 | 0 |
\(\hat {\pi }_{1}\)
| 0.005 | 0.295 | 0.918 | | 0.75 | 0.29 | 0.68 | 0.40 |
- Results of the restricted likelihood ratio tests of the hypothesis \(\mathbf {H}_{0}:{\sigma _{2}^{2}}=0\) for transcripts exceeding the minimum expression level (crit. >8). Numbers of transcripts with a significant variance component for imperfect blending (sign VC) were counted according to the FDR correction level of 5 %. \(\hat {\pi }_{1}\) is the estimated proportion of transcripts with \({\sigma _{2}^{2}}>0\). Simulated data sets s1, s2 and s3 refer to scenarios where none, one third, and all transcripts were associated with a non-zero blending error variance component