Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates

Table 1 Genotypic characterisation of M. tuberculosis clinical isolates used for the investigation into genomic heterogeneity

Isolate name	rpoB^a	Spoligotype classification
R160	Ser531Leu	LCC
R376	Ser531Leu	Haarlem
R458	Ser531Leu	Unknown/unique
R486	Leu533Pro	Beijing
R631	His526Tyr	Unknown/unique
R637	Ser531Leu	Beijing
R641	Leu533Pro	Beijing
R721	Ser531Leu	Beijing
R912	His526Tyr	EAI
R965	Leu533Pro	Beijing
R966	His526Tyr	Beijing
R1035	Ser531Leu	LAM
R1415	His526Tyr	Beijing

LCC low copy clade, EAI East African Indian, LAM Latin American Mediterranean
^aAmino acid change according to the Escherichia coli rpoB gene sequence

ISSN: 1471-2164