Fig. 4

Conserved modules are not shared between the PAG and the cortex. Pairwise comparisons were made of the 16 conserved PAG and 10 conserved cortex modules from Fig. 3. The shading in the table illustrates the percentage overlap as per the inset key. Significance was calculated for the most highly conserved modules for each pairwise comparison and is given alongside the number of overlapping genes per module. Only two modules showed a significant amount of overlap (p < 0.001); the midnight blue PAG with aqua cortex, and the olive PAG with green cortex. However the percentage overlap was very low for both these networks (2 and 10 % respectively), suggesting that the modules identified were specific for the different tissues interrogated