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Fig. 6 | BMC Genomics

Fig. 6

From: The transcriptome of Candida albicans mitochondria and the evolution of organellar transcription units in yeasts

Fig. 6

GC-rich elements in the C. albicans mitochondrial genome. a Schematic representation of the mitochondrial genome of C. albicans with known genes, major genomic regions and transcription units, annotated as in Figs. 1 and 2. The second inverted repeat region (IRb) is identical to IRa in sequence, and was omitted for clarity. Promoter sites are marked by red flags, hairpin elements are denoted as double triangles. Green double triangles are double hairpin (DHE-like) elements, yellow double triangles are DHE-like elements with an insertion between the two hairpins, and blue double triangles are single hairpins. b An example of the double-hairpin element located between transcription units TU3 and TU4. c A single hairpin structure in the noncoding region separating the ATP8 and ATP6 ORFs in a bicistronic mRNA. Sequencing reads mapped to the region are shown in red, grey rectangles highlight the end of ATP8 ORF and the start of the ATP6 ORF. This region is transcribed from the (−) strand of the reference genome, the sequence of the mRNA is thus a reverse complement of the shown reference. d GC-rich elements in the region between the end of transcription unit TU7 and the start of TU8. The promoter of TU8, forming part of the putative DHE-like element is shown in red in the structure, and is boxed in the reference sequence. Italics in the structure denote the nucleotides belonging to the tRNA-Ser_2 (tS(UGA)) sequence. Reads shown in green are sense strand reads, antisense reads are shown in red (both TU7 and TU8 are sense strand transcripts). Read mapping was visualized in CLC Genomics Suite 8 and edited for clarity

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