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Fig. 6 | BMC Genomics

Fig. 6

From: New global analysis of the microRNA transcriptome of primary tumors and lymph node metastases of papillary thyroid cancer

Fig. 6

Down-regulated microRNAs in PTC are differentially expressed in tumor subtypes. A/B: the expressions of the 14 validated down-regulated microRNAs were investigated in in classical and follicular histological variants (a) and in BRAF V600E positive and negative tumor samples (b). For both, unpaired t-test was used to compare the sample types and subtypes. *: significant modulation (p < 0.05) of expression between normal samples and tumors. **: significant modulation of expression between tumor subtypes. Numbers in brackets correspond to the number of available samples in the TCGA dataset for each tissue type

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