Skip to main content
Fig. 1 | BMC Genomics

Fig. 1

From: Investigating inter-chromosomal regulatory relationships through a comprehensive meta-analysis of matched copy number and transcriptomics data sets

Fig. 1

Scatter plot showing, for the 1430 regulators in the database, the number of predicted targets against the number of data sets the regulator shows significant self aCGH/expression correlation. Plot annotated with some of the regulators with large numbers of targets and/or data sets: MED4 - Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription, AZIN1 - Inhibits antizyme-dependent ornithine decarboxylase degradation by binding to antizyme, YWHAZ - Adapter protein implicated in the regulation of a large spectrum of signaling pathways, MRPS28 - Mitochondrial ribosomal protein, POGZ - Zinc finger protein found to interact with the transcription factor SP1, HSBP1 - Overexpression represses the transactivation activity of HSF1, PTS - Biosynthesis of Tetrahydrobiopterin an essential cofactor and regulator of various enzyme activities, TERF2IP - Acts both as a regulator of telomere function and as a transcription regulator, ZBTB43 - Zinc finger and BTB domain containing 43, may be involved in transcriptional regulation, WRB - Receptor, ZCCHC9 - Zinc finger, CCHC domain containing 9, nucleic acid binding, CXCL14 - Belongs to cytokine family which encode proteins involved in immunoregulatory processes, SYT11 - Possibly mediates calcium-dependent regulation of membrane trafficking in synaptic transmission, GNL3L - Essential for ribosomal pre-rRNA processing and cell proliferation, HOXD9 - Belongs to the homeobox family of genes which encode transcription factors, MNS1 - May play a role in the control of meiotic division

Back to article page
\