Fig. 1From: Investigating inter-chromosomal regulatory relationships through a comprehensive meta-analysis of matched copy number and transcriptomics data setsScatter plot showing, for the 1430 regulators in the database, the number of predicted targets against the number of data sets the regulator shows significant self aCGH/expression correlation. Plot annotated with some of the regulators with large numbers of targets and/or data sets: MED4 - Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription, AZIN1 - Inhibits antizyme-dependent ornithine decarboxylase degradation by binding to antizyme, YWHAZ - Adapter protein implicated in the regulation of a large spectrum of signaling pathways, MRPS28 - Mitochondrial ribosomal protein, POGZ - Zinc finger protein found to interact with the transcription factor SP1, HSBP1 - Overexpression represses the transactivation activity of HSF1, PTS - Biosynthesis of Tetrahydrobiopterin an essential cofactor and regulator of various enzyme activities, TERF2IP - Acts both as a regulator of telomere function and as a transcription regulator, ZBTB43 - Zinc finger and BTB domain containing 43, may be involved in transcriptional regulation, WRB - Receptor, ZCCHC9 - Zinc finger, CCHC domain containing 9, nucleic acid binding, CXCL14 - Belongs to cytokine family which encode proteins involved in immunoregulatory processes, SYT11 - Possibly mediates calcium-dependent regulation of membrane trafficking in synaptic transmission, GNL3L - Essential for ribosomal pre-rRNA processing and cell proliferation, HOXD9 - Belongs to the homeobox family of genes which encode transcription factors, MNS1 - May play a role in the control of meiotic divisionBack to article page