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Table 1 Whole exome sequencing mean target coverage depth and percent target coverage statistics of replicate and aggregate data

From: Replicate exome-sequencing in a multiple-generation family: improved interpretation of next-generation sequencing data

WES sample Mean target depth % Target ≥1x % Target ≥10x % Target ≥20x
ID3866     
 Replicate 1 68x 96.2 91.5 86.6
 Replicate 2 65x 96.3 91.9 87.3
 Replicate 3 71x 96.4 92.3 88.3
 Mean ± SE   96.3 ± 0.1 91.9 ± 0.4 87.4 ± 0.8
Aggregate 205x 97.6 95.1 93.8
ID4382     
 Replicate 1 69x 96.5 92.1 87.8
 Replicate 2 61x 96.3 91.6 85.8
 Replicate 3 63x 96.3 91.7 86.4
 Mean ± SE   96.4 ± 0.1 91.8 ± 0.4 86.7 ± 1.0
Aggregate 193x 97.7 95.3 93.9
ID4384     
 Replicate 1 56x 96.0 90.5 83.5
 Replicate 2 68x 96.3 92.0 87.4
 Replicate 3 83x 96.5 92.7 89.4
 Mean ± SE   96.3 ± 0.3 91.7 ± 1.2 86.8 ± 3.0
Aggregate 208x 97.6 95.1 93.8
ID4385     
 Replicate 1 51x 96.2 90.3 83.1
 Replicate 2 86x 96.7 92.9 89.6
 Replicate 3 61x 96.3 91.6 85.7
 Mean ± SE   96.4 ± 0.2 91.6 ± 1.3 86.1 ± 3.2
Aggregate 198x 97.7 95.3 93.9
ID4386     
 Replicate 1 64x 96.4 91.6 86.8
 Replicate 2 69x 96.3 91.9 87.4
 Replicate 3 49x 96.0 90.3 82.1
 Mean ± SE   96.2 ± 0.2 91.2 ± 0.8 85.4 ± 2.9
Aggregate 182x 97.6 94.9 93.5
ID4606     
 Replicate 1 77x 96.5 92.1 87.8
 Replicate 2 48x 96.0 90.1 81.2
 Replicate 3 55x 96.2 90.9 83.7
 Mean ± SE   96.2 ± 0.2 91.0 ± 1.0 84.2 ± 3.3
Aggregate 179x 97.5 95.0 93.5