Fig. 3

CTSS distribution at the aligned CSF1R locus across three species. Figure 3a shows the alignment of the three species at the CSF1R promoter region. H, M and P refer to human, mouse and pig species respectively. Figure 3b shows histograms of the CAGE tag locations in each of mouse, human and pig, aligned based upon the location of start codon (translation start site - TLS) downstream – region shown spans 180 bp upstream of the TLS and 40 bp downstream from it. Horizontal lines underline the binding sites of transcription factors PU.1 (blue lines) and EWS/FUS (red lines) [30]