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Table 1 Up-regulated or down-regulated expression of 24 sex differentiation-related genes in the germ cell-depleted gonads

From: Complete depletion of primordial germ cells in an All-female fish leads to Sex-biased gene expression alteration and sterile All-male occurrence

Hit sequence ID Species Gene name Gene description Gene Up or down-regulation
Exp. Obs.
EU136185.1 squalius pyrenaicus amh anti-Mullerian hormone Unigene7325 T +++
AY090897.1 goldfish ar androgen receptor Cl14013.c2 T +++
NM_001080204.1 black porgy cyp11b 11-beta-hydroxylase Unigene57084 T +++
ACT79291.1 squalius alburnoides dax1 nuclear receptor subfamily 0 group B member 1 Unigene6035 T +++
JQ413415.1 zebrafish dmrt1 doublesex- and mab-3 related transcription factor 1 Cl355.c2 T +++
NM_001005779.2 zebrafish dmrt3 doublesex and mab-3 related transcription factor 3 Unigene44639 T +++
NM_001114668.1 zebrafish gsdf gonadal soma derived factor Cl9466.c1 T +++
AAF43283.1 zebrafish nr5a1a nuclear receptor subfamily 5, group A, member 1a Cl40.c1 T +++
BC078289.1 zebrafish pdgfaa platelet derived growth factor alpha a Cl1048.c1 T +++
NM_001076757.1 zebrafish pdgfab platelet derived growth factor alpha b Cl14024.c1 T +++
Z32814.1 zebrafish pdgfra platelet-derived growth factor receptor, alpha Cl11648.c2 T +++
NP_001070225.1 zebrafish pdgfrb platelet-derived growth factor receptor beta Unigene9549 T +++
XM_860152.2 loach sox8 SRY-related HMG-box 8 Unigene61836 T +++
AAG09814.1 zebrafish sox9a SRY-related HMG-box 9 Cl11561.c1 T +++
AY956415.1 goldfish sox9b SRY-related HMG-box 9 Unigene11888 T +++
JQ217143.1 loach sox10 SRY-related HMG-box 10 Cl19883.c1 T +++
DQ886664.1 zebrafish gata4 GATA-binding protein 4 Cl12384.c1 B +++
BC162638.1 zebrafish wt1a wilms tumor suppressor 1a Cl4953.c1 B +++
BC056276.1 zebrafish ctnnb1 catenin β-1 Unigene4098 O ---
AF020704.1 goldfish cyp19a1a aromatase a Unigene14479 O -
AB531497.1 loach foxl2 forkhead box transcription factor L2 Cl17424.c1 O -
NM_001039621.1 zebrafish fst Follistatin Unigene1876 O ---
AAI24452.1 zebrafish srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Cl17085.c2 O ---
NM_001044939.1 zebrafish srd5a3 3-oxo-5-alpha-steroid 4-dehydrogenase 3 Cl18471.c2 O ---
  1. Exp.: The expected over-expression in testis (T), bipotential gonad (B) or ovary (O) of other vertebrate species; Obs.: The observed up-regulated or down-regulated expression in germ cell-depleted gonads compared with WT gonads. “+++”: Significantly up-regulated expression; “---”: Significantly down-regulated expression; “-”: mildly down-regulated expression