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Fig. 3 | BMC Genomics

Fig. 3

From: Deep sequencing of small RNA facilitates tissue and sex associated microRNA discovery in zebrafish

Fig. 3

Tissue associated expression pattern of the known miRNAs. a Distribution of known miRNA expression levels with respect to number of miRNAs. Numbers of reads are taken as miRNA expression levels and their values are represented in the form of ranges: Level 1: 1–10, Level 2: 10–102, Level 3: 102–103, Level 4: 103–104, Level 5: 104–105, Level 6: 105–106, Level 7:106–107. b Hierarchical clustering plot showing the similarity and differences among the samples. The known mature miRNA profiles of all the tissues were first subjected to TMM normalization and their clustering pattern was determined. There are two major groups seen:(i) The gut and the liver samples (ii) The brain, heart, eye, embryo, ovary and testis samples. The second major group is further divided into three subgroups:(a) The ovary and testis samples were closely placed, followed by the embryo (b) The eye and heart samples (c) The brain samples. c Expression profile of the tissue associated known miRNAs. Differential expression of tissue associated known mature miRNAs. The up-regulated miRNAs are depicted in red colour whereas the downregulated miRNAs are depicted in green colour

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