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Fig. 5 | BMC Genomics

Fig. 5

From: Integrated genomics approach to identify biologically relevant alterations in fewer samples

Fig. 5

Integrative genomic landscape of HNSCC tumors in TCGA dataset. Heatmap representation of hallmark genes in 279 HNSCC samples from TCGA study with frequency of alterations based on integrated CNVs, gene expression and SNVs. Frequency of alterations in the gene based on Cosmic database, Agrawal et al., Stransky et al. and TCGA study are also shown for comparison with integrated analysis. Amplification (red) and deletions (blue) are indicated by filled box, over expression (red) and under expression (blue) are indicated by border line to the box, mis-sense (green), non-sense (black) and in-frame (brown) mutations are indicated by smaller square box

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