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Table 1 Genes with the highest number of promoter:enhancer interactions in RNA Polymerase II ChIA-PET with 8WG16 antibody in human K562 cell line, replicate 1 [21], see associated text for more details on processing of this dataset

From: GenomicInteractions: An R/Bioconductor package for manipulating and investigating chromatin interaction data

Ensembl ID

HGNC Symbol

Number of interactions

Number of promoter:promoter interactions

Number of promoters

Number of promoter:enhancer interactions

Number of enhancers

ENSG00000177000

MTHFR

934

686

7

233

9

ENSG00000011021

CLCN6

901

686

7

208

9

ENSG00000183337

BCOR

2585

2444

1

110

14

ENSG00000137193

PIM1

167

60

1

107

42

ENSG00000007944

MYLIP

721

485

2

97

38

ENSG00000120949

TNFRSF8

198

91

1

84

3

ENSG00000153234

NR4A2

671

541

2

82

5

ENSG00000253276

CCDC71L

303

186

3

76

12

ENSG00000116717

GADD45A

537

317

1

73

12

ENSG00000172216

CEBPB

414

265

8

65

21

  1. A window size of 2.5 kb around TSSs, defined using the FANTOM5 robust tag cluster set, was used to define promoters. Enhancers and other chromatin states were defined using the Genome Segments K562 track. The number of interactions is calculated as the sum of the PET counts of all anchors overlapping the promoter region of a gene