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Fig. 10 | BMC Genomics

Fig. 10

From: Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses

Fig. 10

Immunohistochemistry in colon tissue sections for TNFα protein. In unirradiated colon, TNFα protein is weakly distributed across the section; however, a streak of some visible signals can be seen beneath the intact mucosal epithelial lining (panels a and b, solid white arrow). At day 4 after 7.4-Gy TBI, TNFα staining in the interstitial space from serosa to mucosa and submucosa of the colon exhibits significantly increased TNFα staining. Note the strong streak of TNFα staining in the mucosal region close to the epithelial barrier, forming an interface between swollen/disrupted cells and normal-shaped cells (panels c and d, open arrows)

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