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Table 1 Selected pregnancy associated target genes for differentially expressed miRNAs in the porcine endometrium

From: Expression of microRNAs and isomiRs in the porcine endometrium: implications for gene regulation at the maternal-conceptus interface

Functional category Target genea DE miRNAs
Prostaglandin signaling and metabolism PTGS2 miR-758, miR-16, miR-320, let-7a, miR-199a-3p, miR-203
PTGER2 miR-429
PTGFR miR-23b, miR-92b-3p, miR-205, miR-429
PTGIS miR-449a, miR-150, miR-200a
PTGIR miR-1, miR-205
Inflammatory mediators IL6 let-7e, miR-365-3p, miR-574
IL6R miR-200a, miR-27a/b, miR-24-3p, miR-342, miR-23b, miR-495, let-7a, miR-17, miR-449a
LIF miR-106b-5p, miR-27a/b, miR-17-5p, miR-574
LIFR miR-1, miR-142-3p, miR-342, miR-365-3p, miR-203, miR-30d, miR-27a, miR-23b, miR-205, miR-191, miR-199a-3p
Growth factors, receptors and related proteins IGF1 miR-1, miR-495, miR-186, miR-486, miR-23b, miR-27a, miR-380, miR-30d, miR-361-5p, miR-16, let-7a
IGF1R let-7a, miR-100, miR-200a, miR-186, miR-16, miR-30d, miR-96, miR-495, miR-375
IGFBP1 miR-140-3p, miR-205, let-7a
IGFBP3 miR-374a-5p, miR-449a, miR-1249, let-7a
IGFBP5 miR-1, miR-24-3p, miR-146a-5p, miR-193b-3p, miR-203, miR-27a
VEGFA miR-342, miR-200a, miR-1, miR-1249, miR-186, miR-449a, miR-16, miR-205, miR-203, miR-150, miR-374a-5p, miR-361-5p, miR-17-5p, miR-106b, miR-23b, miR-429
KDR miR-16, miR-200b, miR-23b
Flt1 miR-96, miR-142-3p, miR-200b, miR-200a, miR-374a-5p, miR-193b-3p, miR-17-5p, miR-106b
FGF7 miR-27a, miR-186, miR-495, miR-199b-3p, miR-361-5p, miR-140, miR-16, miR-132, miR-486, miR-17, miR-429
FGF2 miR-16, miR-23b, miR-203, miR-17
SPRED1 miR-1, miR-96, miR-16, mniR-199a-3p, miR-132, miR-142-3p, miR-200c-3p, miR-17-5p, miR-106b, miR-449a, miR-126
Other Wnt4 miR-16, miR-186, miR-24-3p, miR-429
Wnt5a miR-129b, miR-140-3p, miR-374b-5p, miR-200a, miR-92b-3p, miR-365-3p, miR-186, miR-30d, miR-23b, miR-203, miR-205, miR-574
Wnt7a miR-361-5p, miR-16
CTNNB1 miR-150, miR-200a
CDH1 miR-495, let-7a, miR-23b
HoxA10 miR-27a, miR-374b-5p, miR-16
ESR1 miR-1, miR-17-5p, miR-20a, miR-203, miR-129b, miR-193, miR-106b, miR-23b
PGR miR-342, miR-129b, miR-96, miR-23b, miR-140-3p, miR-495
  1. aTarget prediction for DE miRNAs was done using IPA and miRWalk, which incorporate information from several algorithms such as: miRanda, TargetScan, miRDB, RNA22, PICTAR or DIANA-microT and miRwalk. miRNA target genes identified by at least three of these algorithms were considered for analysis