Fig. 5

Heat maps of tissue-to-tissue distances generated by applying the ‘dist’ function in R to the transpose of a matrix, as defined for each heat map. For each heat map, the variability between tissues is measured by the height of the dendrogram branches. The colour key indicates the distance between tissues with red being the least distant (or most correlated) and white being the most distant (or least correlated). a Uses a SNP by tissue matrix containing the paternal allele frequency of all ASE SNP, therefore displaying the correlation of ASE between tissues. b Uses a SNP by tissue matrix in which SNP were assigned “1” if mono-allelic and “0” if not, therefore displaying the correlation of MAE between tissues. c Uses a gene by tissue matrix in which genes classified as maternal were assigned “-0.5”, genes classified as paternal were assigned a value of “0.5” and genes that could not be classified or were not expressed were assigned “0”, therefore displaying the correlation of paternal ASE between tissues. d Uses a gene by tissue matrix in which all genes in “runs” of 5 or more (as defined in methods) were designated a value of “1” and genes not in a run were designated “0”, therefore displaying the between tissue correlation of genes falling into runs of greater than 5 or more expressing the same allele