Down-regulated (MCF7/MCF10A) | |
EIF3E | Translation initiation factor: Decreased eIF3e/Int6 expression causes epithelial-to-mesenchymal transition in breast epithelial cells. |
EIF3M | Translation initiation factor. |
IPO5 | Importin 5: Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. |
RPL7 | Ribosomal protein |
RPL9 | Ribosomal protein |
RPL22L1 | The Ribosomal Protein Rpl22 Controls Ribosome Composition |
RPL26 | ribosomal protein |
NOL10 | Nucleolar Protein 11: Ribosome biogenesis factor. |
NOL11 | Nucleolar Protein 11: Ribosome biogenesis factor. |
DDX1 | Dead Box helicase implicated in mRNA processing |
DHX9 | RNA Helicase A, RHA: Implicated in translation of mRNAs with structured 5′TLs. |
DDX58 | Dead box helicase |
DHX15 | Pre-mRNA-splicing factor ATP-dependent RNA helicase |
EPRS | Glutamyl-Prolyl-tRNA Synthetase |
LARS | leucine-tRNA synthetase |
RARS | Arginyl-tRNA Synthetas |
HEATR1 | HEAT Repeat-Containing Protein 1: Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis. |
RPPH1 | Ribonuclease P RNA Component H1: an endoribonuclease that cleaves tRNA precursor molecules to form the mature 5′ termini. |
RSL24D1 | Involved in the biogenesis of the 60S ribosomal subunit. |
SKIV2L2 | ATP-Dependent RNA Helicase: involved in the 3′-processing of the 7S pre-RNA to the mature 5.8S rRNA. |
Up-regulated (MCF7/MCF10A) | |
ARAF | v-raf murine sarcoma oncogene homolog: May also regulate the TOR signaling cascade. |
EIF5AL1 | Eukaryotic translation initiation factor 5A-like 1 |
RBM38 | RNA-binding protein that specifically binds the 3′-UTR of CDKN1A transcripts. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. |