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Table 4 Transcription factors in CLL regulatory networks after MRA

From: Regulatory network reconstruction reveals genes with prognostic value for chronic lymphocytic leukemia

Network GSE46261 Network GSE39671
Master regulator FET P-value Inter-section set Mode Master regulator FET P-value Inter-section set Mode
CERS6 9.01E-36 40 + EGR3 7.36E-17 39 -
TCF7 1.17E-28 37 - CERS6 8.80E-17 47 +
TLE1 1.66E-16 22 + PHTF1 1.22E-11 37 +
ZNF135 3.97E-15 21 + AEBP1 4.51E-10 30 +
MYBL1 4.33E-13 22 - NR2F6 4.58E-08 20 +
ELK3 3.59E-10 16 + MYBL1 7.17E-08 26 -
AEBP1 1.11E-09 16 + ZNF91 8.43E-08 16 -
GFI1 3.00E-09 13 + TFDP1 3.64E-07 16 +
NCOR2 4.86E-08 12 + TCF7 5.57E-07 42 -
TRPS1 6.00E-08 11 + APEX1 2.00E-06 24 +
TSHZ2 3.55E-07 16 - ZNF354A 3.26E-06 10 +
ARID5B 6.01E-07 9 - SMARCA4 6.54E-06 39 +
NOD2 7.06E-07 17 + Network GSE38611
EGR3 1.20E-06 9 - MYBL1 3.80E-07 6 -
ZNF236 2.13E-06 8 + CERS6 5.90E-06 4 +
HOXB2 2.76E-06 9 + Network GSE22762
BRIP1 3.27E-06 15 - TCF7 3.01E-23 49 -
MTA1 6.51E-06 14 + EGR3 5.25E-14 23 -
Network GSE2466 CERS6 1.21E-11 21 +
KLF7 2.11E-13 23 - MYBL1 3.38E-10 24 -
AFF1 1.79E-08 16 - TCF7L2 3.82E-10 31 -
TCF3 1.26E-07 21 + MYBL2 8.67E-10 23 +
TCF7 1.77E-05 18 - AEBP1 1.89E-09 16 +
TLE1 2.72E-05 8 + TFEC 6.31E-08 12 -
RUNX3 5.22E-05 13 - PHTF1 8.18E-08 29 +
ZNF135 1.10E-04 8 + PBX3 7.17E-07 14 +
KLF10 1.85E-04 6 + EP400 7.72E-07 17 +
CERS6 1.85E-04 6 + PPARD 5.82E-06 25 -