Table 4 Transcription factors in CLL regulatory networks after MRA
Network GSE46261 | Network GSE39671 | ||||||
|---|---|---|---|---|---|---|---|
Master regulator | FET P-value | Inter-section set | Mode | Master regulator | FET P-value | Inter-section set | Mode |
CERS6 | 9.01E-36 | 40 | + | EGR3 | 7.36E-17 | 39 | - |
TCF7 | 1.17E-28 | 37 | - | CERS6 | 8.80E-17 | 47 | + |
TLE1 | 1.66E-16 | 22 | + | PHTF1 | 1.22E-11 | 37 | + |
ZNF135 | 3.97E-15 | 21 | + | AEBP1 | 4.51E-10 | 30 | + |
MYBL1 | 4.33E-13 | 22 | - | NR2F6 | 4.58E-08 | 20 | + |
ELK3 | 3.59E-10 | 16 | + | MYBL1 | 7.17E-08 | 26 | - |
AEBP1 | 1.11E-09 | 16 | + | ZNF91 | 8.43E-08 | 16 | - |
GFI1 | 3.00E-09 | 13 | + | TFDP1 | 3.64E-07 | 16 | + |
NCOR2 | 4.86E-08 | 12 | + | TCF7 | 5.57E-07 | 42 | - |
TRPS1 | 6.00E-08 | 11 | + | APEX1 | 2.00E-06 | 24 | + |
TSHZ2 | 3.55E-07 | 16 | - | ZNF354A | 3.26E-06 | 10 | + |
ARID5B | 6.01E-07 | 9 | - | SMARCA4 | 6.54E-06 | 39 | + |
NOD2 | 7.06E-07 | 17 | + | Network GSE38611 | |||
EGR3 | 1.20E-06 | 9 | - | MYBL1 | 3.80E-07 | 6 | - |
ZNF236 | 2.13E-06 | 8 | + | CERS6 | 5.90E-06 | 4 | + |
HOXB2 | 2.76E-06 | 9 | + | Network GSE22762 | |||
BRIP1 | 3.27E-06 | 15 | - | TCF7 | 3.01E-23 | 49 | - |
MTA1 | 6.51E-06 | 14 | + | EGR3 | 5.25E-14 | 23 | - |
Network GSE2466 | CERS6 | 1.21E-11 | 21 | + | |||
KLF7 | 2.11E-13 | 23 | - | MYBL1 | 3.38E-10 | 24 | - |
AFF1 | 1.79E-08 | 16 | - | TCF7L2 | 3.82E-10 | 31 | - |
TCF3 | 1.26E-07 | 21 | + | MYBL2 | 8.67E-10 | 23 | + |
TCF7 | 1.77E-05 | 18 | - | AEBP1 | 1.89E-09 | 16 | + |
TLE1 | 2.72E-05 | 8 | + | TFEC | 6.31E-08 | 12 | - |
RUNX3 | 5.22E-05 | 13 | - | PHTF1 | 8.18E-08 | 29 | + |
ZNF135 | 1.10E-04 | 8 | + | PBX3 | 7.17E-07 | 14 | + |
KLF10 | 1.85E-04 | 6 | + | EP400 | 7.72E-07 | 17 | + |
CERS6 | 1.85E-04 | 6 | + | PPARD | 5.82E-06 | 25 | - |