TY - JOUR AU - Levy, Roei AU - Mott, Richard F. AU - Iraqi, Fuad A. AU - Gabet, Yankel PY - 2015 DA - 2015/11/26 TI - Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture JO - BMC Genomics SP - 1013 VL - 16 IS - 1 AB - The microstructure of trabecular bone is a composite trait governed by a complex interaction of multiple genetic determinants. Identifying these genetic factors should significantly improve our ability to predict of osteoporosis and its associated risks. Genetic mapping using collaborative cross mice (CC), a genetically diverse recombinant inbred mouse reference panel, offers a powerful tool to identify causal loci at a resolution under one mega base-pairs, with a relatively small cohort size. SN - 1471-2164 UR - https://doi.org/10.1186/s12864-015-2213-x DO - 10.1186/s12864-015-2213-x ID - Levy2015 ER -