Fig. 1

Characterization of L. major intracellular growth and proportion of RNA from the parasite. Mouse macrophages infected with L. major were collected at 4, 24, 48, and 72 hpi and subjected to transcriptional profiling by RNA-seq. An average of 87 % of macrophages were infected across all samples. Bar plots are used to illustrate a the average number of parasites observed per 100 host cells and b the average percentage of trimmed RNA-seq reads that map to the L. major genome. Standard errors bars are shown. No statistically significant changes were observed between timepoints