Table 2 TopGO enrichment of biological process terms in differentially expressed gene clusters

A. Moderate down regulated

GO:0055114

oxidation-reduction process

769

75

29.4

GO:0008272

sulfate transport

10

5

0.38

GO:0006081

cellular aldehyde metabolic process

9

3

0.34

GO:0032787

monocarboxylic acid metabolic process

70

8

2.68

GO:0006749

glutathione metabolic process

14

3

0.54

GO:0005978

glycogen biosynthetic process

6

2

0.23

GO:1901700

response to oxygen-containing compound

6

2

0.23

GO:0044270

cellular nitrogen compound catabolic process

385

17

14.72

GO:0046700

heterocycle catabolic process

386

17

14.76

GO:0006099

tricarboxylic acid cycle

18

3

0.69

GO:0044262

cellular carbohydrate metabolic process

41

6

1.57

GO:1901361

organic cyclic compound catabolic process

388

17

14.83

GO:0006730

one-carbon metabolic process

8

2

0.31

GO:1901292

nucleoside phosphate catabolic process

357

13

13.65

GO:0055085

transmembrane transport

576

34

22.02

GO:0043648

dicarboxylic acid metabolic process

11

2

0.42

GO:0007205

protein kinase C-activating G-protein coupled receptor signaling pathway

11

2

0.42

GO:0044106

cellular amine metabolic process

20

3

0.76

GO:0006979

response to oxidative stress

28

3

1.07

B. Strong down regulated

GO:0006952

defense response

14

2

0.01

GO:1902476

chloride transmembrane transport

6

1

0

GO:0042742

defense response to bacterium

9

1

0.01

C. Moderate up regulated

GO:0071702

organic substance transport

266

27

10.92

GO:0008610

lipid biosynthetic process

103

13

4.23

GO:0016192

vesicle-mediated transport

114

15

4.68

GO:0043623

cellular protein complex assembly

32

7

1.31

GO:0042398

cellular modified amino acid biosynthetic process

20

5

0.82

GO:0007229

integrin-mediated signaling pathway

8

3

0.33

GO:0006195

purine nucleotide catabolic process

341

24

14

GO:0006955

immune response

17

4

0.7

GO:0042742

defense response to bacterium

9

3

0.37

GO:0032940

secretion by cell

18

4

0.74

GO:0009207

purine ribonucleoside triphosphate catabolic process

340

24

13.96

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

11

3

0.45

GO:0030029

actin filament-based process

35

6

1.44

GO:0010466

negative regulation of peptidase activity

24

4

0.99

GO:0006108

malate metabolic process

5

2

0.21

GO:0007267

cell-cell signaling

14

3

0.57

GO:0034613

cellular protein localization

136

11

5.58

GO:0007264

small GTPase mediated signal transduction

189

12

7.76

GO:0006470

protein dephosphorylation

54

6

2.22

GO:0019751

polyol metabolic process

6

2

0.25

GO:1901617

organic hydroxy compound biosynthetic process

6

2

0.25

GO:0016051

carbohydrate biosynthetic process

26

4

1.07

GO:0006457

protein folding

80

7

3.28

GO:0007017

microtubule-based process

81

7

3.33

GO:0046130

purine ribonucleoside catabolic process

340

24

13.96

GO:0048285

organelle fission

34

4

1.4

GO:0000165

MAPK cascade

9

2

0.37

GO:0006270

DNA replication initiation

9

2

0.37

GO:0033014

tetrapyrrole biosynthetic process

10

2

0.41

GO:0046939

nucleotide phosphorylation

11

2

0.45

GO:0016998

cell wall macromolecule catabolic process

11

2

0.45

GO:0000902

cell morphogenesis

11

2

0.45

GO:0044262

cellular carbohydrate metabolic process

41

4

1.68

GO:0006879

cellular iron ion homeostasis

13

2

0.53

GO:0006826

iron ion transport

13

2

0.53

GO:0046854

phosphatidylinositol phosphorylation

13

2

0.53

D. Strong up regulated

GO:0016042

lipid catabolic process

51

2

0.11

GO:0034314

Arp2/3 complex-mediated actin nucleation

7

1

0.01

GO:0070588

calcium ion transmembrane transport

17

1

0.04

GO:0032319

regulation of Rho GTPase activity

24

1

0.05