Table 4 Comparison of genome-wide mutation rate estimates
From: The properties of spontaneous mutations in the opportunistic pathogen Pseudomonas aeruginosa
| Â | Wild type | MMR-deficient | Â | ||
|---|---|---|---|---|---|
Organism | per genome per generation | per nucleotide per generation | per genome per generation | per nucleotide per generation | Reference |
P. aeruginosa, mutation accumulation | 0.52 × 10−3 | 0.79 × 10−10 | 0.14 | 2.11 × 10−8 | this study |
P. aeruginosa, mutation accumulation | n/a | n/a | 0.18 | 2.95 × 10−8 | ref. [20] |
E. coli, mutation accumulation | 0.92 × 10−3 | 1.99 × 10−10 | 0.13 | 2.75 × 10−8 | ref. [4] |
E. coli, synonymous sites | 0.41 × 10−3 | 0.89 × 10−10 | n/a | n/a | ref. [61] |
S. typhimurium, mutation accumulation | 3.4 × 10−3 | 7.0 × 10−10 | 0.09 | 2.0 × 10−8 | ref. [19] |
S. cerevisiae, mutation accumulation | 5.84 × 10−3 | 4.8 × 10−10 | 0.90 | 7.4 × 10−8 | ref. [62] |
S. cerevisiae, mutation accumulation | 4.01 × 10−3 | 3.3 × 10−10 | n/a | n/a | ref. [3] |