Deep sequencing of Danish Holstein dairy cattle for variant detection and insight into potential loss-of-function variants in protein coding genes

Table 6 Numbers of LoF variants before filtering and putative deleterious LoF variants after filtering

LoF^hom variants were homozygous in all four sequenced Danish Holstein cows; LoF^het variants for which at least one of the four sequenced cows was heterozygous; AH¹ LoF variants for which none of the 288 sequenced Holstein animals from the 1000 bull genomes project was homozygous; Consistent are concordantly called both in the four Danish Holstein cows and the 288 Holstein animals; Inconsistent variants called as discordant variant types (SNP as indel or indel as SNP) between the four Danish Holstein cows and the 288 bulls from the 1000 bull genomes project; Novel variants are not annotated in dbSNP build133

ISSN: 1471-2164