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Fig. 2 | BMC Genomics

Fig. 2

From: Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington’s disease are not reflected in mutant Huntingtin inclusion prevalence

Fig. 2

Pathways implicated by the gene expression differences in YAC128 mouse striata. List of differentially expressed genes were generated by t-test using a nominal p < 0.01; DAVID was used for the pathway analysis with a pathway filter q < 0.05. The pathway node size is proportional to gene membership and the edges joining nodes are weighted by gene overlap between nodes. Terms have been clustered into groups that contain 90 % genetic similarity on average. The most significant term of the cluster has been displayed. These terms have been further clustered at a level of 50 % average genetic similarity and colour-coded by cluster

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