Fig. 6

Breakpoints of the four common duplications on chromosome V compared to their flanking repeats. Four independent populations contain a duplication of a region between positions 19,294,839 and 19,838,583 on chromosome V. These duplications are the product of unequal crossing-over between two 1,031 bp repeats that are 96 % identical and flank the duplication. The figure shows polymorphic sites between the two repeats, and the nucleotides flanking the breakpoints of the four duplications. The sequences of the upstream and downstream repeats are displayed on the topmost (orange) and lowermost (yellow) rows, respectively. The sequence of the new repeat in the center of the tandem duplication is shown for strains 16B, 66E, 16E, and C2, and the correspondence to the original flanking repeats is indicated by color. The duplication breakpoint is inferred to be between the sequence that corresponds to the downstream repeat (yellow) and the upstream repeat (orange)