Skip to main content

Table 3 Frequencies of CNVs in experimental C. elegans lines at different time intervals of population expansion using single-worm PCR

From: Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegans

Pop ID. generation Type of rearrangements Individuals sampled Number positive for rearrangement Expectec Hardy-Weinberg frequency Average copy-number qPCR oaCGH
16B.80 Duplication 19 0 0.00 1.00 - -
16B.140 47 0 0.00 1.00 0.86 -
16B.200 43 28 0.41 1.41 1.02 1.19
16E.80 Duplication 30 1 0.02 1.02 1.08 -
16E.140 30 25 0.59 1.59 1.58 -
16E.200 18 18 1.00 2.00 2.39 2.08
66E.140 Duplication 27 10 0.20 1.20 1.23 -
66E.200 28 22 0.54 1.54 1.67 1.33
16A.140 Deletion 30 30 1.00 0.00 0.00 -
16A.200 27 27 1.00 0.00 0.00 0.05
16D.80 Deletion 18 15 0.64 0.36 0.22 -
16D.140 18 28 1.00 0.00 0.000232 -
16D.200 29 29 1.00 0.00 0.000738 0.05
66B.80 Deletion 32 0 0.00 1.00 0.73 -
66B.140 15 9 0.40 0.60 0.40 -
66B.200 28 28 1.00 0.00 0.0000269 0.04
  1. Pop ID.Generation refers to the experimental population number and the number of generations of population expansion when sampled. Column 5 displays the frequency of individuals with the rearrangement assuming Hardy-Weinberg equilibrium. Columns 6–8 show the average copy-number per haploid genome for three methods, namely single-worm PCR, qPCR and oaCGH