Fig. 1

Alignment profiles of short peptides to parental vs non-parental KO-families. Comparison of alignment behavior (Left panel) when the short peptides align to members of their parent KO-families (Right panel) when short peptides align to members of their non-parent KO-families. While hits to same KO-family members have high proportion of alignment-identity above 80 %, but a major fraction of hits still remain in the range of 40–80 % (for both left & right panel) and makes it difficult to discriminate between true and false positive hits. Hexbin colors within the graph are proportional to their frequency or members within the bin. Member frequency and color relationship is depicted in the arrow-headed color bar