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Fig. 2 | BMC Genomics

Fig. 2

From: Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection

Fig. 2

Virulence of P. aeruginosa RP isolates in comparison with prototype strains in murine model. C57Bl/6NCrlBR mice were infected with 1-2*106 CFU/lung P. aeruginosa RP1, RP45, RP73, PAO1 and PA14 strains embedded in agar beads. Mortality induced by bacteremia (black) and survival (light gray) was evaluated on challenged mice. Clearance (white) and capacity to establish chronic infection (dark gray) were determined on surviving mice after 14 days. The data show the percentage of mice infected with single P. aeruginosa strains analyzed in two to three independent experiments. Statistical significance by Chi-square test is indicated: *P < 0.05, **P < 0.01, ***P < 0.001

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