Fig. 2
From: ChromContact: A web tool for analyzing spatial contact of chromosomes from Hi-C data
Two examples of long-range enhancer–promoter interactions in ZEB2 and PAX6 loci. Only the cell type with the most significant interaction is shown in each example. For each example, there are four tracks (from the top): (i) contact profile at 10-kb resolution obtained from Hi-C data; (ii) profile for H3K4me1; and (iii) profile for DNase I hypersensitivity sites; and (iv) gene annotations. The anchors, which contain the transcription start sites of the respective genes, are indicated by dark-colored highlights in the contact profiles. The positions of the enhancers are indicated by rounded rectangles. a A 800-kb genomic interval around the human ZEB2 locus (genome assembly hg19). b A 800-kb genomic interval around the human PAX6 locus (genome assembly hg19)