Category | Term | Total genes in term | Union targets in term | miRNAs in term | Score |
---|---|---|---|---|---|
Reactome | Axon_guidance | 266 | 154 | 28 | 3.983 |
Reactome | Developmental_biology | 494 | 229 | 28 | 3.716 |
KEGG | Pathways_in_cancer | 325 | 173 | 28 | 2.951 |
Reactome | L1cam_interactions | 94 | 61 | 26 | 2.77 |
KEGG | Mapk_signaling_pathway | 272 | 135 | 29 | 2.466 |
KEGG | Wnt_signaling_pathway | 150 | 91 | 28 | 2.466 |
Go_mf | Protein_binding_transcription_factor_activity | 369 | 164 | 28 | 2.334 |
Reactome | Signalling_by_ngf | 221 | 118 | 26 | 2.243 |
PID | Direct_p53_effectors | 137 | 65 | 27 | 2.062 |
KEGG | Focal_adhesion | 199 | 99 | 27 | 1.992 |
Reactome | Hemostasis | 467 | 191 | 29 | 1.989 |
KEGG | Endocytosis | 201 | 102 | 27 | 1.944 |
KEGG | Prostate_cancer | 89 | 49 | 26 | 1.941 |
KEGG | Neurotrophin_signaling_pathway | 127 | 71 | 27 | 1.909 |
PID | Pdgfr-beta_signaling_pathway | 126 | 69 | 27 | 1.9 |
PID | Regulation_of_nuclear_smad2_3_signaling | 82 | 52 | 27 | 1.847 |
Reactome | Neuronal_system | 289 | 120 | 28 | 1.837 |
KEGG | Glioma | 65 | 35 | 27 | 1.836 |
PID | Signaling_events_mediated_by_hepatocyte_growth_factor_receptor_(c-met) | 77 | 50 | 26 | 1.74 |
KEGG | Regulation_of_actin_cytoskeleton | 213 | 100 | 26 | 1.73 |
PID | E2f_transcription_factor_network | 73 | 44 | 25 | 1.717 |
Reactome | Transmission_across_chemical_synapses | 190 | 85 | 28 | 1.701 |
PID | C-myb_transcription_factor_network | 81 | 46 | 24 | 1.683 |
Reactome | Nuclear_receptor_transcription_pathway | 51 | 27 | 26 | 1.66 |
PID | Ephb_forward_signaling | 36 | 27 | 22 | 1.619 |
KEGG | Erbb_signaling_pathway | 87 | 48 | 27 | 1.614 |
KEGG | Melanoma | 71 | 34 | 27 | 1.594 |
KEGG | Melanogenesis | 101 | 55 | 28 | 1.582 |
KEGG | Small_cell_lung_cancer | 84 | 43 | 26 | 1.563 |
PID | Notch_signaling_pathway | 59 | 37 | 25 | 1.55 |
KEGG | Tgf-beta_signaling_pathway | 84 | 47 | 27 | 1.545 |
PID | Tcr_signaling_in_naive_cd4 + _t_cells | 64 | 36 | 24 | 1.544 |
Reactome | Signaling_by_egfr | 109 | 62 | 25 | 1.521 |
KEGG | Pancreatic_cancer | 70 | 41 | 26 | 1.518 |
KEGG | Fc_gamma_r-mediated_phagocytosis | 94 | 47 | 25 | 1.506 |
PID | Coregulation_of_androgen_receptor_activity | 57 | 35 | 26 | 1.5 |
KEGG | Adherens_junction | 73 | 44 | 26 | 1.499 |
KEGG | Tight_junction | 132 | 61 | 27 | 1.498 |
PID | Shp2_signaling | 54 | 34 | 25 | 1.485 |
PID | P73_transcription_factor_network | 73 | 34 | 25 | 1.462 |
Reactome | Rho_gtpase_cycle | 124 | 58 | 25 | 1.455 |
Reactome | Signaling_by_fgfr | 114 | 57 | 26 | 1.447 |
KEGG | Chronic_myeloid_leukemia | 73 | 39 | 25 | 1.432 |
KEGG | Renal_cell_carcinoma | 70 | 40 | 25 | 1.428 |
PID | Ap-1_transcription_factor_network | 69 | 41 | 25 | 1.41 |
Reactome | G1_phase | 38 | 23 | 22 | 1.387 |
KEGG | Dilated_cardiomyopathy | 90 | 42 | 24 | 1.384 |
Reactome | Signaling_by_interleukins | 106 | 47 | 25 | 1.371 |
Reactome | Downstream_signal_transduction | 93 | 53 | 25 | 1.354 |
KEGG | Bacterial_invasion_of_epithelial_cells | 70 | 39 | 24 | 1.349 |
Reactome | Adaptive_immune_system | 482 | 162 | 28 | 1.347 |
PID | Integrins_in_angiogenesis | 74 | 46 | 25 | 1.342 |
KEGG | Ubiquitin_mediated_proteolysis | 135 | 70 | 24 | 1.337 |
PID | Hif-1-alpha_transcription_factor_network | 65 | 35 | 26 | 1.337 |
KEGG | Oocyte_meiosis | 112 | 52 | 27 | 1.334 |
PID | Cxcr4-mediated_signaling_events | 102 | 54 | 25 | 1.323 |
Reactome | Cd28_co-stimulation | 31 | 20 | 21 | 1.316 |
PID | Role_of_calcineurin-dependent_nfat_signaling_in_lymphocytes | 55 | 35 | 23 | 1.31 |
KEGG | Cell_cycle | 124 | 55 | 25 | 1.29 |
PID | Cdc42_signaling_events | 70 | 40 | 25 | 1.29 |
KEGG | P53_signaling_pathway | 68 | 38 | 24 | 1.289 |
PID | Posttranslational_regulation_of_adherens_junction_stability_and_dissassembly | 48 | 29 | 24 | 1.28 |
Reactome | Platelet_activation_signaling_and_aggregation | 205 | 85 | 27 | 1.278 |
PID | Regulation_of_retinoblastoma_protein | 64 | 35 | 27 | 1.275 |
PID | Bcr_signaling_pathway | 68 | 36 | 25 | 1.274 |
PID | Signaling_events_regulated_by_ret_tyrosine_kinase | 38 | 22 | 22 | 1.266 |
Reactome | Circadian_clock | 33 | 20 | 24 | 1.254 |
KEGG | Long-term_potentiation | 70 | 40 | 25 | 1.252 |
Reactome | Cytokine_signaling_in_immune_system | 220 | 77 | 27 | 1.236 |
KEGG | Shigellosis | 61 | 36 | 23 | 1.233 |
KEGG | Vascular_smooth_muscle_contraction | 126 | 49 | 26 | 1.21 |
KEGG | Gnrh_signaling_pathway | 101 | 45 | 27 | 1.21 |
Reactome | Mitotic_g1-g1_s_phases | 135 | 46 | 25 | 1.195 |
PID | Signaling_events_mediated_by_hdac_class_i | 67 | 31 | 22 | 1.183 |
PID | Foxo_family_signaling | 49 | 31 | 25 | 1.179 |
PID | Signaling_events_mediated_by_VEGFR | 68 | 41 | 24 | 1.163 |
KEGG | Insulin_signaling_pathway | 137 | 63 | 28 | 1.153 |
PID | Igf1_pathway | 29 | 21 | 23 | 1.147 |
Reactome | Cell_cycle_mitotic | 330 | 95 | 27 | 1.146 |
PID | Validated_targets_of_c-myc_transcriptional_repression | 63 | 31 | 25 | 1.137 |
Reactome | P75_ntr_receptor-mediated_signalling | 86 | 40 | 23 | 1.135 |
KEGG | Colorectal_cancer | 62 | 38 | 25 | 1.13 |
Reactome | Cell_death_signalling_via_nrage_nrif_and_nade | 64 | 32 | 23 | 1.126 |
Reactome | Transmembrane_transport_of_small_molecules | 427 | 145 | 28 | 1.125 |
PID | Atf-2_transcription_factor_network | 58 | 34 | 25 | 1.124 |
PID | Ifn-gamma_pathway | 42 | 30 | 24 | 1.12 |
Reactome | Metabolism_of_liPIDs_and_lipoproteins | 292 | 89 | 27 | 1.119 |
KEGG | Calcium_signaling_pathway | 177 | 73 | 26 | 1.113 |
Reactome | G_alpha_(12_13)_signalling_events | 77 | 36 | 22 | 1.111 |
PID | Syndecan-1-mediated_signaling_events | 46 | 27 | 22 | 1.11 |
PID | Lpa_receptor_mediated_events | 66 | 37 | 23 | 1.109 |
Reactome | Fatty_acid_triacylglycerol_and_ketone_body_metabolism | 112 | 40 | 21 | 1.096 |
PID | E-cadherin signaling in_the_nascent_adherens_junction | 38 | 27 | 22 | 1.094 |
PID | Bmp_receptor_signaling | 42 | 28 | 21 | 1.09 |
KEGG | Chemokine_signaling_pathway | 189 | 77 | 28 | 1.088 |
Reactome | Nrage_signals_death_through_jnk | 47 | 25 | 23 | 1.086 |
Reactome | Cell-cell_communication | 129 | 60 | 25 | 1.083 |
KEGG | T_cell_receptor_signaling_pathway | 108 | 50 | 25 | 1.083 |
Reactome | Antigen_processing_ubiquitination_proteasome_degradation | 213 | 86 | 26 | 1.078 |
PID | Fgf_signaling_pathway | 59 | 35 | 24 | 1.061 |