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Table 3 Description of datasets used to validate CANEapp performance to estimate differential gene expression

From: CANEapp: a user-friendly application for automated next generation transcriptomic data analysis

Name

Organism

Experimental groups

N of samples

RNA selection protocol

Library preparation

Single or paired-end

GEO

Transcriptomic changes in hippocampi of Alzheimer’s disease patients

Homo sapiens

Alzheimer’s disease vs age- and sex-matched neurologically normal controls

4 vs 4

Ribo-depletion

Illumina directional small RNA prep

single

GSE67333

Transcriptomic changes in embryonic and adult mouse cortex

Mus musculus

E17 cortex vs adult cortex

4 vs 3

Poly-A selection

Illumina mRNA-Seq prep

paired

GSE39866

SEQC Rat liver toxicogenomics study

Rattus norvegicus

N-Nitrosodimethylamine, Aflatoxin B1 vs Vehicle treatments

3 vs 3

Poly-A selection

Illumina TruSeq RNA

paired

GSE55347

3 vs 4