Skip to main content

Table 3 LD50 estimation

From: Using host-pathogen protein interactions to identify and characterize Francisella tularensis virulence factors

Strain

Log10(CFU) 95 % confidence intervals

CFU 95 % confidence intervals

Median

Lower

Upper

Median

Lower

Upper

Wild type

0.42

0.02

0.81

2.62

1.06

6.43

ΔFTT0482c

1.77a

1.46

2.08

59.14a

28.82

121.04

ΔFTT0902

-1.14

-2.01

-0.52

0.07

0.01

0.30

ΔFTT1538c

0.97a

0.57

1.38

9.26a

3.68

24.16

ΔFTT1564

0.63

0.46

0.80

4.29

2.86

6.26

ΔFTT1597

1.59a

1.13

2.07

38.66a

13.36

116.48

  1. Estimated 50 % lethal dose (LD50) values for the F. tularensis subsp. tularensis Schu S4 wild-type strain and the following five mutant strains: ΔFTT0482c, ΔFTT0902, ΔFTT1538c, ΔFTT1564, and ΔFTT1597. CFU, colony-forming units. aLD50 values above the wild-type LD50 value