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Table 4 Enrichment of GO terms for human proteins interacting with F. tularensis

From: Using host-pathogen protein interactions to identify and characterize Francisella tularensis virulence factors

 

GO term ID

GO term description

Number of proteins

p-value

FDR

Cellular localization

GO:0005793

Endoplasmic reticulum-Golgi intermediate compartment

4

2.7∙10-3

0.04

GO:0005788

Endoplasmic reticulum lumen

6

1.7∙10-3

0.03

GO:0005801

Cis-Golgi network

3

3.6∙10-3

0.05

GO:0005720

Nuclear heterochromatin

3

3.6∙10-3

0.05

GO:0042470

Melanosome

7

9.5∙10-5

0.00

GO:0042588

Zymogen granule

3

3.3∙10-3

0.01

GO:0035097

Histone methyltransferase complex

4

3.8∙10-3

0.05

GO:0031519

PcG protein complex

3

5.1∙10-3

0.06

Molecular function

GO:0051082

Unfolded protein binding

6

1.9∙10-3

0.18

GO:0019904

Protein domain specific binding

14

3.6∙10-3

0.18

  1. FDR, false discovery rate calculated using Benjamini and Hochberg multiple test correction [40]; GO, Gene Ontology