Fig. 6

Nucleolar associated genes are differentially expressed in RBS cells. Expression levels of genes located in nucleolar associated domains (NADs, indicated on the left) is shown in a heatmap for corrected cells (C) and RBS cells (M) treated with either D-Leu (D) or L-Leu (L) for 3 or 24 h. Within each domain, genes tend to show a similar pattern, although some domains show increased expression in the corrected cells while others show reduced expression. In general these patterns are unaffected by the addition of L-leucine. Data can be found in Additional file 2: Table S13