Fig. 7
Characteristics of A. millepora caspase-X. a A schematic diagram of the A. millepora caspase-X protein. The pseudo protease domain, CASc*, and a protease domain, CASc, are indicated by blue and red boxes, respectively. Abbreviation: CASc, Caspase, interleukin-1 ÎČ converting enzyme homologues. b The alignments of amino acid sequences of CASc* and CASc motifs of A. millepora caspase-X with that of human c-FLIP and caspase-8 proteins. Identical and similar amino acids in the motifs are shown in red and blue, respectively. The histidine and cysteine residues outlined by red boxes are crucial amino acids for protease activity, whereas the amino acid residues outlined by blue boxes indicate the exchanged amino acids from histidine and cysteine. c The numbers indicate the percentage identity and similarity between two domains, respectively