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Fig. 3 | BMC Genomics

Fig. 3

From: Pangenome-wide and molecular evolution analyses of the Pseudomonas aeruginosa species

Fig. 3

Molecular evolution of the P. aeruginosa pangenome. a Histogram showing the distribution of omega (ω) values across the P. aeruginosa pangenome. The light blue histogram shows the original distribution with the tendency towards values indicating purifying selection (shift to left from neutrality). The superposed light red histogram indicates the Z-scores for the selection of genes with ω significantly different than 1. Those with significant ω <1 were considered to be under strong purifying selection for functional analysis, and those with significant ω >1 were selected to be under strong positive selection for the MLST approach. b Scatter plot to represent the distribution of normalized dN and dS rates for all gene families detected in the P. aeruginosa pangenome. Gene families under strong purifying selection are highlighted in blue, whereas gene families under positive selection (ω >2) are highlighted in red. The set of gene family candidates for MLST under strong positive selection are highlighted in green. The diagonal dashed line indicates the boundary for neutrality

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